Stabilization of Homocysteine Concentration in Whole Blood
نویسندگان
چکیده
منابع مشابه
Stabilization of mRNA expression in whole blood samples.
BACKGROUND Accurate quantification of mRNA in whole blood is made difficult by the simultaneous degradation of gene transcripts and unintended gene induction caused by sample handling or uncontrolled activation of coagulation. This study was designed to compare a new blood collection tube (PAXgene Blood RNA System) and a companion sample preparation reagent set with a traditional sample collect...
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ment. We saw no systematic error associated with a plot of the residuals (data not shown). The linear model accounted for the data, and the underlying assumptions (linearity, stable variance) of the model have not been violated. The upper limit of linearity was 3.377 mmol/L (700 mg/L), although we routinely used a linear calibration up to 1.930 mmol/L (400 mg/L), which encompassed almost all of...
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reference interval value. In addition, 46 serum samples from healthy individuals were tested using the EFC-cAMP method (mean 94.4%, median 94.5%, and SD 6.8%). Results for the normal samples were 80% to 106% of the control (data not shown). This EFC-cAMP assay is a nonradioactive surrogate for RIAcAMP for studying antibody-mediated increases in cAMP concentrations in response to activation of t...
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Mefloquine, as a racemic mixture, is used for the treatment and prophylaxis of malaria. Stereoselective pharmacodynamic and pharmacokinetic differences has been observed for mefloquine. In this study a modified stereoselective HPLC method is presented for determination of mefloquine (MFQ) enantiomers in whole blood. The assay involved liquid-liquid extraction of MFQ from biological fluids with ...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1998
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/44.7.1567